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COVID-19 and Vaccination Status in Lysosomal Storage Diseases: A Single-Center Experience
OBJECTIVE: Coronavirus disease 2019 (COVID-19) causes significant morbidity and mortality in individuals with chronic disease. There is not enough information about the course of coronavirus disease in lysosomal storage diseases. This study aimed to evaluate coronavirus disease vaccination status an...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Turkish Pediatrics Association
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210971/ https://www.ncbi.nlm.nih.gov/pubmed/37144258 http://dx.doi.org/10.5152/TurkArchPediatr.2023.22233 |
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author | Yoldaş Çelik, Merve Canda, Ebru Yazıcı, Havva Erdem, Fehime Yazıcı Özkaya, Pınar Bal Sahbudak, Zumrut Kalkan Uçar, Sema Çoker, Mahmut |
author_facet | Yoldaş Çelik, Merve Canda, Ebru Yazıcı, Havva Erdem, Fehime Yazıcı Özkaya, Pınar Bal Sahbudak, Zumrut Kalkan Uçar, Sema Çoker, Mahmut |
author_sort | Yoldaş Çelik, Merve |
collection | PubMed |
description | OBJECTIVE: Coronavirus disease 2019 (COVID-19) causes significant morbidity and mortality in individuals with chronic disease. There is not enough information about the course of coronavirus disease in lysosomal storage diseases. This study aimed to evaluate coronavirus disease vaccination status and the impact of coronavirus disease on lysosomal storage disease. MATERIALS AND METHODS: The study included 87 lysosomal storage disease patients. The patients’ diagnoses were Gaucher, mucopolysaccharidosis I, II, IVA, VI, VII, Fabry, and Pompe. A questionnaire assessing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, coronavirus disease symptoms, and vaccine status was administered in person or by phone calls. RESULTS: The number of coronavirus disease positive patients was 8 (9.1%). Only 2 patients were treated in the intensive care unit. Other coronavirus disease patients had mild symptoms and stayed in-home quarantine. Patients over 12 years of age could receive a COVID-19 vaccine. 63.5% of those aged ≥12 years were vaccinated. CONCLUSION: Lysosomal storage disease patients did not have an increased risk of COVID-19 compared to the healthy population, despite the chronic inflammatory disease. Vaccination of lysosomal storage disease patients will be protective against severe coronavirus disease. |
format | Online Article Text |
id | pubmed-10210971 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Turkish Pediatrics Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-102109712023-05-26 COVID-19 and Vaccination Status in Lysosomal Storage Diseases: A Single-Center Experience Yoldaş Çelik, Merve Canda, Ebru Yazıcı, Havva Erdem, Fehime Yazıcı Özkaya, Pınar Bal Sahbudak, Zumrut Kalkan Uçar, Sema Çoker, Mahmut Turk Arch Pediatr Original Article OBJECTIVE: Coronavirus disease 2019 (COVID-19) causes significant morbidity and mortality in individuals with chronic disease. There is not enough information about the course of coronavirus disease in lysosomal storage diseases. This study aimed to evaluate coronavirus disease vaccination status and the impact of coronavirus disease on lysosomal storage disease. MATERIALS AND METHODS: The study included 87 lysosomal storage disease patients. The patients’ diagnoses were Gaucher, mucopolysaccharidosis I, II, IVA, VI, VII, Fabry, and Pompe. A questionnaire assessing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, coronavirus disease symptoms, and vaccine status was administered in person or by phone calls. RESULTS: The number of coronavirus disease positive patients was 8 (9.1%). Only 2 patients were treated in the intensive care unit. Other coronavirus disease patients had mild symptoms and stayed in-home quarantine. Patients over 12 years of age could receive a COVID-19 vaccine. 63.5% of those aged ≥12 years were vaccinated. CONCLUSION: Lysosomal storage disease patients did not have an increased risk of COVID-19 compared to the healthy population, despite the chronic inflammatory disease. Vaccination of lysosomal storage disease patients will be protective against severe coronavirus disease. Turkish Pediatrics Association 2023-05-01 /pmc/articles/PMC10210971/ /pubmed/37144258 http://dx.doi.org/10.5152/TurkArchPediatr.2023.22233 Text en 2023 authors https://creativecommons.org/licenses/by-nc/4.0/ Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Original Article Yoldaş Çelik, Merve Canda, Ebru Yazıcı, Havva Erdem, Fehime Yazıcı Özkaya, Pınar Bal Sahbudak, Zumrut Kalkan Uçar, Sema Çoker, Mahmut COVID-19 and Vaccination Status in Lysosomal Storage Diseases: A Single-Center Experience |
title | COVID-19 and Vaccination Status in Lysosomal Storage Diseases: A Single-Center Experience |
title_full | COVID-19 and Vaccination Status in Lysosomal Storage Diseases: A Single-Center Experience |
title_fullStr | COVID-19 and Vaccination Status in Lysosomal Storage Diseases: A Single-Center Experience |
title_full_unstemmed | COVID-19 and Vaccination Status in Lysosomal Storage Diseases: A Single-Center Experience |
title_short | COVID-19 and Vaccination Status in Lysosomal Storage Diseases: A Single-Center Experience |
title_sort | covid-19 and vaccination status in lysosomal storage diseases: a single-center experience |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210971/ https://www.ncbi.nlm.nih.gov/pubmed/37144258 http://dx.doi.org/10.5152/TurkArchPediatr.2023.22233 |
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