A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8

Small animal models have been a challenge for the study of SARS-CoV-2 transmission, with most investigators using golden hamsters or ferrets. Mice have the advantages of low cost, wide availability, less regulatory and husbandry challenges, and the existence of a versatile reagent and genetic toolbo...

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Detalles Bibliográficos
Autores principales: Rodriguez-Rodriguez, Bruno A., Ciabattoni, Grace O., Duerr, Ralf, Valero-Jimenez, Ana M., Yeung, Stephen T., Crosse, Keaton M., Schinlever, Austin R., Bernard-Raichon, Lucie, Rodriguez Galvan, Joaquin, McGrath, Marisa E., Vashee, Sanjay, Xue, Yong, Loomis, Cynthia A., Khanna, Kamal M., Cadwell, Ken, Desvignes, Ludovic, Frieman, Matthew B., Ortigoza, Mila B., Dittmann, Meike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10211296/
https://www.ncbi.nlm.nih.gov/pubmed/37230979
http://dx.doi.org/10.1038/s41467-023-38783-0

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