Knowledge-guided data mining on the standardized architecture of NRPS: Subtypes, novel motifs, and sequence entanglements

Non-ribosomal peptide synthetase (NRPS) is a diverse family of biosynthetic enzymes for the assembly of bioactive peptides. Despite advances in microbial sequencing, the lack of a consistent standard for annotating NRPS domains and modules has made data-driven discoveries challenging. To address thi...

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Detalles Bibliográficos
Autores principales: He, Ruolin, Zhang, Jinyu, Shao, Yuanzhe, Gu, Shaohua, Song, Chen, Qian, Long, Yin, Wen-Bing, Li, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212144/
https://www.ncbi.nlm.nih.gov/pubmed/37186644
http://dx.doi.org/10.1371/journal.pcbi.1011100

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