A multi‐omics perspective of CAR T cell therapy

As omics technologies, including genomics, epigenomics, transcriptomics, T cell receptor‐repertorie profiling, proteomics, metabolomics and microbiomics, have provided valuable insights into CAR T cell therapy, in our recent review, we discuss these multidimensional profiling technologies in CAR T c...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jingwen, Chen, Yamei, Han, Leng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212274/
https://www.ncbi.nlm.nih.gov/pubmed/37228183
http://dx.doi.org/10.1002/ctm2.1274
Descripción
Sumario:As omics technologies, including genomics, epigenomics, transcriptomics, T cell receptor‐repertorie profiling, proteomics, metabolomics and microbiomics, have provided valuable insights into CAR T cell therapy, in our recent review, we discuss these multidimensional profiling technologies in CAR T cell research, and their potential to identify tumor‐specific antigens and molecular characteristics associated with anti‐tumour effects and toxicities.

Ejemplares similares