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The compleX balancing act of controlling X-chromosome dosage and how it impacts mammalian germline development
In female mammals, the two X chromosomes are subject to epigenetic gene regulation in order to balance X-linked gene dosage with autosomes and in relation to males, which have one X and one Y chromosome. This is achieved by an intricate interplay of several processes; X-chromosome inactivation and r...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212525/ https://www.ncbi.nlm.nih.gov/pubmed/37096944 http://dx.doi.org/10.1042/BCJ20220450 |