Possible Ambiguity in Interpretation Between Immunoglobulin G4-Related Disease (IgG4-RD) and Sarcoidosis in a Post-COVID-19 Pandemic

A 36-year-old lady presented with fever, cough, maculopapular rash, painless sialadenitis, episcleritis, and arthralgia of more than 10 months, occurring in episodes since she tested positive for COVID-19 in 2020. Her symptoms were well controlled with corticosteroid and immunosuppressant therapy. H...

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Autores principales: Gurunathan, Rajesh, Dhanasekaran, Pavithra, Devaprasad, Dedeepiya, Jacob, Sheba SK, Abraham, Babu K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212579/
https://www.ncbi.nlm.nih.gov/pubmed/37252493
http://dx.doi.org/10.7759/cureus.38124
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author Gurunathan, Rajesh
Dhanasekaran, Pavithra
Devaprasad, Dedeepiya
Jacob, Sheba SK
Abraham, Babu K
author_facet Gurunathan, Rajesh
Dhanasekaran, Pavithra
Devaprasad, Dedeepiya
Jacob, Sheba SK
Abraham, Babu K
author_sort Gurunathan, Rajesh
collection PubMed
description A 36-year-old lady presented with fever, cough, maculopapular rash, painless sialadenitis, episcleritis, and arthralgia of more than 10 months, occurring in episodes since she tested positive for COVID-19 in 2020. Her symptoms were well controlled with corticosteroid and immunosuppressant therapy. Her clinical presentation and findings on bronchoscopy resembled that of sarcoidosis. However, the bronchial biopsy histopathology ruled out sarcoidosis. An increased serum immunoglobulin G4 level and its possible association with COVID-19 raises the question of whether the possibility of immunoglobulin G4-related disease (IgG4-RD) could be entertained.
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spelling pubmed-102125792023-05-26 Possible Ambiguity in Interpretation Between Immunoglobulin G4-Related Disease (IgG4-RD) and Sarcoidosis in a Post-COVID-19 Pandemic Gurunathan, Rajesh Dhanasekaran, Pavithra Devaprasad, Dedeepiya Jacob, Sheba SK Abraham, Babu K Cureus Internal Medicine A 36-year-old lady presented with fever, cough, maculopapular rash, painless sialadenitis, episcleritis, and arthralgia of more than 10 months, occurring in episodes since she tested positive for COVID-19 in 2020. Her symptoms were well controlled with corticosteroid and immunosuppressant therapy. Her clinical presentation and findings on bronchoscopy resembled that of sarcoidosis. However, the bronchial biopsy histopathology ruled out sarcoidosis. An increased serum immunoglobulin G4 level and its possible association with COVID-19 raises the question of whether the possibility of immunoglobulin G4-related disease (IgG4-RD) could be entertained. Cureus 2023-04-25 /pmc/articles/PMC10212579/ /pubmed/37252493 http://dx.doi.org/10.7759/cureus.38124 Text en Copyright © 2023, Gurunathan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Gurunathan, Rajesh
Dhanasekaran, Pavithra
Devaprasad, Dedeepiya
Jacob, Sheba SK
Abraham, Babu K
Possible Ambiguity in Interpretation Between Immunoglobulin G4-Related Disease (IgG4-RD) and Sarcoidosis in a Post-COVID-19 Pandemic
title Possible Ambiguity in Interpretation Between Immunoglobulin G4-Related Disease (IgG4-RD) and Sarcoidosis in a Post-COVID-19 Pandemic
title_full Possible Ambiguity in Interpretation Between Immunoglobulin G4-Related Disease (IgG4-RD) and Sarcoidosis in a Post-COVID-19 Pandemic
title_fullStr Possible Ambiguity in Interpretation Between Immunoglobulin G4-Related Disease (IgG4-RD) and Sarcoidosis in a Post-COVID-19 Pandemic
title_full_unstemmed Possible Ambiguity in Interpretation Between Immunoglobulin G4-Related Disease (IgG4-RD) and Sarcoidosis in a Post-COVID-19 Pandemic
title_short Possible Ambiguity in Interpretation Between Immunoglobulin G4-Related Disease (IgG4-RD) and Sarcoidosis in a Post-COVID-19 Pandemic
title_sort possible ambiguity in interpretation between immunoglobulin g4-related disease (igg4-rd) and sarcoidosis in a post-covid-19 pandemic
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212579/
https://www.ncbi.nlm.nih.gov/pubmed/37252493
http://dx.doi.org/10.7759/cureus.38124
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