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Safely Implementing a Program of Pure Laparoscopic Donor Right Hepatectomy: The Experience From a Southeast Asian Center

Laparoscopic donor right hepatectomy (LDRH) is a technically challenging procedure. There is increasing evidence demonstrating the safety of LDRH in high-volume expert centers. We report our center’s experience in implementing an LDRH program in a small- to medium-sized transplantation program. METH...

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Autores principales: Law, Jia-Hao, Tan, Chun Han Nigel, Tan, Kah Hwee Jarrod, Gao, Yujia, Pang, Ning Qi, Bonney, Glenn Kunnath, Iyer, Shridhar Ganpathi, Soubrane, Olivier, Kow, Wei Chieh Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212616/
https://www.ncbi.nlm.nih.gov/pubmed/37250490
http://dx.doi.org/10.1097/TXD.0000000000001486
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author Law, Jia-Hao
Tan, Chun Han Nigel
Tan, Kah Hwee Jarrod
Gao, Yujia
Pang, Ning Qi
Bonney, Glenn Kunnath
Iyer, Shridhar Ganpathi
Soubrane, Olivier
Kow, Wei Chieh Alfred
author_facet Law, Jia-Hao
Tan, Chun Han Nigel
Tan, Kah Hwee Jarrod
Gao, Yujia
Pang, Ning Qi
Bonney, Glenn Kunnath
Iyer, Shridhar Ganpathi
Soubrane, Olivier
Kow, Wei Chieh Alfred
author_sort Law, Jia-Hao
collection PubMed
description Laparoscopic donor right hepatectomy (LDRH) is a technically challenging procedure. There is increasing evidence demonstrating the safety of LDRH in high-volume expert centers. We report our center’s experience in implementing an LDRH program in a small- to medium-sized transplantation program. METHODS: Our center systematically introduced a laparoscopic hepatectomy program in 2006. We started with minor wedge resections followed by major hepatectomies with increasing complexities. In 2017, we performed our first laparoscopic living donor left lateral sectionectomy. Since 2018, we have performed 8 cases of right lobe living donor hepatectomy (laparoscopy-assisted: 4 and pure laparoscopic: 4). RESULTS: The median operative time was 418 (298–540) min, whereas the median blood loss was 300 (150–900) mL. Two patients (25%) had surgical drain placed intraoperatively. The median length of stay was 5 (3–8) d, and the median time to return to work was 55 (24–90) d. None of the donors sustained any long-term morbidity or mortality. CONCLUSIONS: Small- to medium-sized transplant programs face unique challenges in adopting LDRH. Progressive introduction of complex laparoscopic surgery, a mature living donor liver transplantation program, appropriate patient selection, and the invitation of an expert to proctor the LDRH are necessary to ensure success.
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spelling pubmed-102126162023-05-26 Safely Implementing a Program of Pure Laparoscopic Donor Right Hepatectomy: The Experience From a Southeast Asian Center Law, Jia-Hao Tan, Chun Han Nigel Tan, Kah Hwee Jarrod Gao, Yujia Pang, Ning Qi Bonney, Glenn Kunnath Iyer, Shridhar Ganpathi Soubrane, Olivier Kow, Wei Chieh Alfred Transplant Direct Liver Transplantation Laparoscopic donor right hepatectomy (LDRH) is a technically challenging procedure. There is increasing evidence demonstrating the safety of LDRH in high-volume expert centers. We report our center’s experience in implementing an LDRH program in a small- to medium-sized transplantation program. METHODS: Our center systematically introduced a laparoscopic hepatectomy program in 2006. We started with minor wedge resections followed by major hepatectomies with increasing complexities. In 2017, we performed our first laparoscopic living donor left lateral sectionectomy. Since 2018, we have performed 8 cases of right lobe living donor hepatectomy (laparoscopy-assisted: 4 and pure laparoscopic: 4). RESULTS: The median operative time was 418 (298–540) min, whereas the median blood loss was 300 (150–900) mL. Two patients (25%) had surgical drain placed intraoperatively. The median length of stay was 5 (3–8) d, and the median time to return to work was 55 (24–90) d. None of the donors sustained any long-term morbidity or mortality. CONCLUSIONS: Small- to medium-sized transplant programs face unique challenges in adopting LDRH. Progressive introduction of complex laparoscopic surgery, a mature living donor liver transplantation program, appropriate patient selection, and the invitation of an expert to proctor the LDRH are necessary to ensure success. Lippincott Williams & Wilkins 2023-05-24 /pmc/articles/PMC10212616/ /pubmed/37250490 http://dx.doi.org/10.1097/TXD.0000000000001486 Text en Copyright © 2023 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Liver Transplantation
Law, Jia-Hao
Tan, Chun Han Nigel
Tan, Kah Hwee Jarrod
Gao, Yujia
Pang, Ning Qi
Bonney, Glenn Kunnath
Iyer, Shridhar Ganpathi
Soubrane, Olivier
Kow, Wei Chieh Alfred
Safely Implementing a Program of Pure Laparoscopic Donor Right Hepatectomy: The Experience From a Southeast Asian Center
title Safely Implementing a Program of Pure Laparoscopic Donor Right Hepatectomy: The Experience From a Southeast Asian Center
title_full Safely Implementing a Program of Pure Laparoscopic Donor Right Hepatectomy: The Experience From a Southeast Asian Center
title_fullStr Safely Implementing a Program of Pure Laparoscopic Donor Right Hepatectomy: The Experience From a Southeast Asian Center
title_full_unstemmed Safely Implementing a Program of Pure Laparoscopic Donor Right Hepatectomy: The Experience From a Southeast Asian Center
title_short Safely Implementing a Program of Pure Laparoscopic Donor Right Hepatectomy: The Experience From a Southeast Asian Center
title_sort safely implementing a program of pure laparoscopic donor right hepatectomy: the experience from a southeast asian center
topic Liver Transplantation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212616/
https://www.ncbi.nlm.nih.gov/pubmed/37250490
http://dx.doi.org/10.1097/TXD.0000000000001486
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