The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review

The cribriform-morular variant of papillary thyroid carcinoma (CMV-PTC) is now designated as morular cribriform thyroid carcinoma (CMTC) according to the 5(th) edition of the World Health Organization (WHO) Classification of Thyroid Tumors. CMTC can appear within a familial adenomatous polyposis (FA...

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Detalles Bibliográficos
Autores principales: Lyu, Sucong, Zhong, Guoqiang, Chen, Hui, Li, Jin, Li, Mingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212671/
https://www.ncbi.nlm.nih.gov/pubmed/37251554
http://dx.doi.org/10.1155/2023/6222432
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author Lyu, Sucong
Zhong, Guoqiang
Chen, Hui
Li, Jin
Li, Mingsong
author_facet Lyu, Sucong
Zhong, Guoqiang
Chen, Hui
Li, Jin
Li, Mingsong
author_sort Lyu, Sucong
collection PubMed
description The cribriform-morular variant of papillary thyroid carcinoma (CMV-PTC) is now designated as morular cribriform thyroid carcinoma (CMTC) according to the 5(th) edition of the World Health Organization (WHO) Classification of Thyroid Tumors. CMTC can appear within a familial adenomatous polyposis (FAP) or be sporadic. We report the first case of a young female patient in China who was diagnosed with FAP and CMTC with a mutation in exon 16 of the APC gene underlying the disease. The main purpose of this case report is to provide a special pathological type of thyroid tumors, which is expected to be helpful for clinical work in the future.
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spelling pubmed-102126712023-05-26 The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review Lyu, Sucong Zhong, Guoqiang Chen, Hui Li, Jin Li, Mingsong Case Rep Gastrointest Med Case Report The cribriform-morular variant of papillary thyroid carcinoma (CMV-PTC) is now designated as morular cribriform thyroid carcinoma (CMTC) according to the 5(th) edition of the World Health Organization (WHO) Classification of Thyroid Tumors. CMTC can appear within a familial adenomatous polyposis (FAP) or be sporadic. We report the first case of a young female patient in China who was diagnosed with FAP and CMTC with a mutation in exon 16 of the APC gene underlying the disease. The main purpose of this case report is to provide a special pathological type of thyroid tumors, which is expected to be helpful for clinical work in the future. Hindawi 2023-05-18 /pmc/articles/PMC10212671/ /pubmed/37251554 http://dx.doi.org/10.1155/2023/6222432 Text en Copyright © 2023 Sucong Lyu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lyu, Sucong
Zhong, Guoqiang
Chen, Hui
Li, Jin
Li, Mingsong
The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title_full The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title_fullStr The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title_full_unstemmed The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title_short The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title_sort first case of cribriform-morular thyroid carcinoma and fap with apc gene mutation in china: a case report and brief review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212671/
https://www.ncbi.nlm.nih.gov/pubmed/37251554
http://dx.doi.org/10.1155/2023/6222432
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