Genome editing HLA alleles for a pilot immunocompatible hESC line in a Chinese hESC bank for cell therapies

Robust allogeneic immune reactions after transplantation impede the translational pace of human embryonic stem cells (hESCs)‐based therapies. Selective genetic editing of human leucocyte antigen (HLA) molecules has been proposed to generate hESCs with immunocompatibility, which, however, has not bee...

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Detalles Bibliográficos
Autores principales: Ji, Tian‐Tian, Niu, Shuai‐Shuai, Fang, Ming‐Hui, Xu, Ling‐Xue, Wang, Xin, Zou, Jun, Xu, Fei, Zhang, Meng, Niu, Rui, Wu, Jun, Wang, Lei, Li, Zhi‐Kun, Yang, Yong‐Guang, Hao, Jie, Li, Wei, Hu, Zheng, Zhou, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212709/
https://www.ncbi.nlm.nih.gov/pubmed/37199039
http://dx.doi.org/10.1111/cpr.13471

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