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Generation of human otic neuronal organoids using pluripotent stem cells

Otic neurons, also known as spiral ganglion neurons (SGNs) in mammalian cochlea, transmit electrical signals from sensory hair cells to cochlear nuclei of the auditory system. SGNs are sensitive to toxic insults, vulnerable to get irreversible damaged and hardly regenerate after damage, causing pers...

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Detalles Bibliográficos
Autores principales: Sun, Gaoying, Tang, Mingming, Wang, Xinyue, Li, Da, Liu, Wenwen, Qi, Jianhuan, Wang, Haibo, Hu, Baoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212712/
https://www.ncbi.nlm.nih.gov/pubmed/36825797
http://dx.doi.org/10.1111/cpr.13434