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GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity

The transfer of intact mitochondria between heterogeneous cell types has been confirmed in various settings, including cancer. However, the functional implications of mitochondria transfer on tumor biology are poorly understood. Here we show that mitochondria transfer is a prevalent phenomenon in gl...

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Detalles Bibliográficos
Autores principales: Watson, Dionysios C., Bayik, Defne, Storevik, Simon, Moreino, Shannon Sherwin, Sprowls, Samuel A., Han, Jianhua, Augustsson, Mina Thue, Lauko, Adam, Sravya, Palavalasa, Røsland, Gro Vatne, Troike, Katie, Tronstad, Karl Johan, Wang, Sabrina, Sarnow, Katharina, Kay, Kristen, Lunavat, Taral R., Silver, Daniel J., Dayal, Sahil, Joseph, Justin Vareecal, Mulkearns-Hubert, Erin, Ystaas, Lars Andreas Rømo, Deshpande, Gauravi, Guyon, Joris, Zhou, Yadi, Magaut, Capucine R., Seder, Juliana, Neises, Laura, Williford, Sarah E., Meiser, Johannes, Scott, Andrew J., Sajjakulnukit, Peter, Mears, Jason A., Bjerkvig, Rolf, Chakraborty, Abhishek, Daubon, Thomas, Cheng, Feixiong, Lyssiotis, Costas A., Wahl, Daniel R., Hjelmeland, Anita B., Hossain, Jubayer A., Miletic, Hrvoje, Lathia, Justin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212766/
https://www.ncbi.nlm.nih.gov/pubmed/37169842
http://dx.doi.org/10.1038/s43018-023-00556-5

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