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Ex vivo drug response heterogeneity reveals personalized therapeutic strategies for patients with multiple myeloma

Multiple myeloma (MM) is a plasma cell malignancy defined by complex genetics and extensive patient heterogeneity. Despite a growing arsenal of approved therapies, MM remains incurable and in need of guidelines to identify effective personalized treatments. Here, we survey the ex vivo drug and immun...

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Detalles Bibliográficos
Autores principales: Kropivsek, Klara, Kachel, Paul, Goetze, Sandra, Wegmann, Rebekka, Festl, Yasmin, Severin, Yannik, Hale, Benjamin D., Mena, Julien, van Drogen, Audrey, Dietliker, Nadja, Tchinda, Joëlle, Wollscheid, Bernd, Manz, Markus G., Snijder, Berend
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212768/
https://www.ncbi.nlm.nih.gov/pubmed/37081258
http://dx.doi.org/10.1038/s43018-023-00544-9