Rapid TCR:Epitope Ranker (RAPTER): a primary human T cell reactivity screening assay pairing epitope and TCR at single cell resolution

Identifying epitopes that T cells respond to is critical for understanding T cell-mediated immunity. Traditional multimer and other single cell assays often require large blood volumes and/or expensive HLA-specific reagents and provide limited phenotypic and functional information. Here, we present...

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Detalles Bibliográficos
Autores principales: Deering, Raquel P., Blumenberg, Lili, Li, Lianjie, Dhanik, Ankur, Jeong, Se, Pourpe, Stephane, Song, Hang, Boucher, Lauren, Ragunathan, Shoba, Li, Yanxia, Zhong, Maggie, Kuhnert, Jessica, Adler, Christina, Hawkins, Peter, Gupta, Namita T., Moore, Michael, Ni, Min, Hansen, Johanna, Wei, Yi, Thurston, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212918/
https://www.ncbi.nlm.nih.gov/pubmed/37231180
http://dx.doi.org/10.1038/s41598-023-35710-7

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