Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche

The cellular organization of gastrointestinal crypts is orchestrated by different cells of the stromal niche but available in vitro models fail to fully recapitulate the interplay between epithelium and stroma. Here, we establish a colon assembloid system comprising the epithelium and diverse stroma...

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Detalles Bibliográficos
Autores principales: Lin, Manqiang, Hartl, Kimberly, Heuberger, Julian, Beccaceci, Giulia, Berger, Hilmar, Li, Hao, Liu, Lichao, Müllerke, Stefanie, Conrad, Thomas, Heymann, Felix, Woehler, Andrew, Tacke, Frank, Rajewsky, Nikolaus, Sigal, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212920/
https://www.ncbi.nlm.nih.gov/pubmed/37230989
http://dx.doi.org/10.1038/s41467-023-38780-3

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