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Maximizing protein production by keeping cells at optimal secretory stress levels using real-time control approaches
Optimizing the production of recombinant proteins is a problem of major industrial and pharmaceutical importance. Secretion of the protein by the host cell considerably simplifies downstream purification processes. However, for many proteins, this is also the limiting production step. Current soluti...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212943/ https://www.ncbi.nlm.nih.gov/pubmed/37231013 http://dx.doi.org/10.1038/s41467-023-38807-9 |