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A computational method for cell type-specific expression quantitative trait loci mapping using bulk RNA-seq data

Mapping cell type-specific gene expression quantitative trait loci (ct-eQTLs) is a powerful way to investigate the genetic basis of complex traits. A popular method for ct-eQTL mapping is to assess the interaction between the genotype of a genetic locus and the abundance of a specific cell type usin...

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Detalles Bibliográficos
Autores principales: Little, Paul, Liu, Si, Zhabotynsky, Vasyl, Li, Yun, Lin, Dan-Yu, Sun, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212972/
https://www.ncbi.nlm.nih.gov/pubmed/37231002
http://dx.doi.org/10.1038/s41467-023-38795-w

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