microRNA-132 regulates gene expression programs involved in microglial homeostasis

microRNA-132 (miR-132), a known neuronal regulator, is one of the most robustly downregulated microRNAs (miRNAs) in the brain of Alzheimer’s disease (AD) patients. Increasing miR-132 in AD mouse brain ameliorates amyloid and Tau pathologies, and also restores adult hippocampal neurogenesis and memor...

Descripción completa

Detalles Bibliográficos
Autores principales: Walgrave, Hannah, Penning, Amber, Tosoni, Giorgia, Snoeck, Sarah, Davie, Kristofer, Davis, Emma, Wolfs, Leen, Sierksma, Annerieke, Mars, Mayte, Bu, Taofeng, Thrupp, Nicola, Zhou, Lujia, Moechars, Diederik, Mancuso, Renzo, Fiers, Mark, Howden, Andrew J.M., De Strooper, Bart, Salta, Evgenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213004/
https://www.ncbi.nlm.nih.gov/pubmed/37250784
http://dx.doi.org/10.1016/j.isci.2023.106829

Ejemplares similares

Ejemplares similares