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Simultaneous selection of multiple important single nucleotide polymorphisms in familial genome wide association studies data

We propose a resampling-based fast variable selection technique for detecting relevant single nucleotide polymorphisms (SNP) in a multi-marker mixed effect model. Due to computational complexity, current practice primarily involves testing the effect of one SNP at a time, commonly termed as ‘single...

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Detalles Bibliográficos
Autores principales: Majumdar, Subhabrata, Basu, Saonli, McGue, Matt, Chatterjee, Snigdhansu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213008/
https://www.ncbi.nlm.nih.gov/pubmed/37231056
http://dx.doi.org/10.1038/s41598-023-35379-y

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