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Simultaneous selection of multiple important single nucleotide polymorphisms in familial genome wide association studies data
We propose a resampling-based fast variable selection technique for detecting relevant single nucleotide polymorphisms (SNP) in a multi-marker mixed effect model. Due to computational complexity, current practice primarily involves testing the effect of one SNP at a time, commonly termed as ‘single...
Autores principales: | Majumdar, Subhabrata, Basu, Saonli, McGue, Matt, Chatterjee, Snigdhansu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213008/ https://www.ncbi.nlm.nih.gov/pubmed/37231056 http://dx.doi.org/10.1038/s41598-023-35379-y |
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