CDK4/6 inhibitors and the pRB-E2F1 axis suppress PVR and PD-L1 expression in triple-negative breast cancer

Immune-checkpoint (IC) modulators like the poliovirus receptor (PVR) and programmed death ligand 1 (PD-L1) attenuate innate and adaptive immune responses and are potential therapeutic targets for diverse malignancies, including triple-negative breast cancer (TNBC). The retinoblastoma tumor suppresso...

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Detalles Bibliográficos
Autores principales: Shrestha, Mariusz, Wang, Dong-Yu, Ben-David, Yaacov, Zacksenhaus, Eldad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213015/
https://www.ncbi.nlm.nih.gov/pubmed/37230983
http://dx.doi.org/10.1038/s41389-023-00475-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213015/
https://www.ncbi.nlm.nih.gov/pubmed/37230983
http://dx.doi.org/10.1038/s41389-023-00475-1

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