Bre1/RNF20 promotes Rad51-mediated strand exchange and antagonizes the Srs2/FBH1 helicases

Central to homologous recombination (HR) is the assembly of Rad51 recombinase on single-strand DNA (ssDNA), forming the Rad51-ssDNA filament. How the Rad51 filament is efficiently established and sustained remains partially understood. Here, we find that the yeast ubiquitin ligase Bre1 and its human...

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Detalles Bibliográficos
Autores principales: Liu, Guangxue, Li, Jimin, He, Boxue, Yan, Jiaqi, Zhao, Jingyu, Wang, Xuejie, Zhao, Xiaocong, Xu, Jingyan, Wu, Yeyao, Zhang, Simin, Gan, Xiaoli, Zhou, Chun, Li, Xiangpan, Zhang, Xinghua, Chen, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213050/
https://www.ncbi.nlm.nih.gov/pubmed/37230987
http://dx.doi.org/10.1038/s41467-023-38617-z

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