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Mitochondrial Replication Assay (MIRA) for Efficient in situ Quantification of Nascent mtDNA and Protein Interactions with Nascent mtDNA (mitoSIRF)

Mitochondria play decisive roles in bioenergetics and intracellular communication. These organelles contain a circular mitochondrial DNA (mtDNA) genome that is duplicated within one to two hours by a mitochondrial replisome, independently from the nuclear replisome. mtDNA stability is regulated in p...

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Detalles Bibliográficos
Autores principales: Lozen, Macy, Chen, Yue, Boisvert, Rebecca A., Schlacher, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213078/
https://www.ncbi.nlm.nih.gov/pubmed/37251092
http://dx.doi.org/10.21769/BioProtoc.4680