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Peripheralized sepiapterin reductase inhibition as a safe analgesic therapy
The development of novel analgesics for chronic pain in the last 2 decades has proven virtually intractable, typically failing due to lack of efficacy and dose-limiting side effects. Identified through unbiased gene expression profiling experiments in rats and confirmed by human genome-wide associat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213231/ https://www.ncbi.nlm.nih.gov/pubmed/37251335 http://dx.doi.org/10.3389/fphar.2023.1173599 |