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Xerna™ TME Panel is a machine learning-based transcriptomic biomarker designed to predict therapeutic response in multiple cancers

INTRODUCTION: Most predictive biomarkers approved for clinical use measure single analytes such as genetic alteration or protein overexpression. We developed and validated a novel biomarker with the aim of achieving broad clinical utility. The Xerna™ TME Panel is a pan-tumor, RNA expression-based cl...

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Detalles Bibliográficos
Autores principales: Uhlik, Mark, Pointing, Daniel, Iyer, Seema, Ausec, Luka, Štajdohar, Miha, Cvitkovič, Robert, Žganec, Matjaž, Culm, Kerry, Santos, Valerie Chamberlain, Pytowski, Bronislaw, Malafa, Mokenge, Liu, Hong, Krieg, Arthur M., Lee, Jeeyun, Rosengarten, Rafael, Benjamin, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213262/
https://www.ncbi.nlm.nih.gov/pubmed/37251949
http://dx.doi.org/10.3389/fonc.2023.1158345