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Antibacterial and wound-healing action of Ulmo honey (Eucryphia cordifolia) of differing degrees of purity

INTRODUCTION: Antibacterial properties of honey vary according to its floral origin; few studies report the percentage of pollen types in honey, making it difficult to reproduce and compare the results. This study compares the antibacterial and wound-healing properties of three kinds of monofloral U...

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Autores principales: Muñoz, Mariela, del Sol, Mariano, Vásquez, Bélgica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213365/
https://www.ncbi.nlm.nih.gov/pubmed/37252390
http://dx.doi.org/10.3389/fvets.2023.1172025
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author Muñoz, Mariela
del Sol, Mariano
Vásquez, Bélgica
author_facet Muñoz, Mariela
del Sol, Mariano
Vásquez, Bélgica
author_sort Muñoz, Mariela
collection PubMed
description INTRODUCTION: Antibacterial properties of honey vary according to its floral origin; few studies report the percentage of pollen types in honey, making it difficult to reproduce and compare the results. This study compares the antibacterial and wound-healing properties of three kinds of monofloral Ulmo honey with different percentages of pollen from Eucryphia cordifolia. METHODS: The pollen percentage of the honey was determined by melissopalynological analysis, and they were classified into three groups: M1 (52.77% of pollen from Eucryphia cordifolia), M2 (68.41%), and M3 (82.80%). They were subjected to chemical analysis and agar diffusion test against Staphylococcus aureus. A total of 20 healthy adult guinea pigs (Cavia porcellus) of both sexes were randomly assigned to four groups for experimental burn skin wound (uninfected) production and treatment with Ulmo honey. On day 10 post-injury, biopsies were obtained, and histological analysis was performed to assess wound-healing capacity following the treatment with honey. RESULTS: The chemical analysis showed that M3 differed significantly from M1 in terms of pH (P = 0.020), moisture (P = 0.020), total sugars (P = 0.034), and total solids (P = 0.020). Both strains of Staphylococcus aureus were susceptible to M1 and M2 at 40% w/v but were resistant to M3 at all concentrations. All groups (I–IV) were in the initial proliferative phase, with complete or partial re-epithelialization of the epidermis. DISCUSSION: The antibacterial activity showed a wide range of variation in the different types of honey studied, with no significant differences between wound healing and pollen percentage in the groups studied. Higher pH and the absence of Tineo in M3 conferred a lower antibacterial capacity but not a lower wound healing capacity. Despite its variability in the percentage of Eucryphia cordifolia like primary pollen in Ulmo's monofloral honey, this has the same properties in relation to wound healing.
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spelling pubmed-102133652023-05-27 Antibacterial and wound-healing action of Ulmo honey (Eucryphia cordifolia) of differing degrees of purity Muñoz, Mariela del Sol, Mariano Vásquez, Bélgica Front Vet Sci Veterinary Science INTRODUCTION: Antibacterial properties of honey vary according to its floral origin; few studies report the percentage of pollen types in honey, making it difficult to reproduce and compare the results. This study compares the antibacterial and wound-healing properties of three kinds of monofloral Ulmo honey with different percentages of pollen from Eucryphia cordifolia. METHODS: The pollen percentage of the honey was determined by melissopalynological analysis, and they were classified into three groups: M1 (52.77% of pollen from Eucryphia cordifolia), M2 (68.41%), and M3 (82.80%). They were subjected to chemical analysis and agar diffusion test against Staphylococcus aureus. A total of 20 healthy adult guinea pigs (Cavia porcellus) of both sexes were randomly assigned to four groups for experimental burn skin wound (uninfected) production and treatment with Ulmo honey. On day 10 post-injury, biopsies were obtained, and histological analysis was performed to assess wound-healing capacity following the treatment with honey. RESULTS: The chemical analysis showed that M3 differed significantly from M1 in terms of pH (P = 0.020), moisture (P = 0.020), total sugars (P = 0.034), and total solids (P = 0.020). Both strains of Staphylococcus aureus were susceptible to M1 and M2 at 40% w/v but were resistant to M3 at all concentrations. All groups (I–IV) were in the initial proliferative phase, with complete or partial re-epithelialization of the epidermis. DISCUSSION: The antibacterial activity showed a wide range of variation in the different types of honey studied, with no significant differences between wound healing and pollen percentage in the groups studied. Higher pH and the absence of Tineo in M3 conferred a lower antibacterial capacity but not a lower wound healing capacity. Despite its variability in the percentage of Eucryphia cordifolia like primary pollen in Ulmo's monofloral honey, this has the same properties in relation to wound healing. Frontiers Media S.A. 2023-05-12 /pmc/articles/PMC10213365/ /pubmed/37252390 http://dx.doi.org/10.3389/fvets.2023.1172025 Text en Copyright © 2023 Muñoz, del Sol and Vásquez. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Muñoz, Mariela
del Sol, Mariano
Vásquez, Bélgica
Antibacterial and wound-healing action of Ulmo honey (Eucryphia cordifolia) of differing degrees of purity
title Antibacterial and wound-healing action of Ulmo honey (Eucryphia cordifolia) of differing degrees of purity
title_full Antibacterial and wound-healing action of Ulmo honey (Eucryphia cordifolia) of differing degrees of purity
title_fullStr Antibacterial and wound-healing action of Ulmo honey (Eucryphia cordifolia) of differing degrees of purity
title_full_unstemmed Antibacterial and wound-healing action of Ulmo honey (Eucryphia cordifolia) of differing degrees of purity
title_short Antibacterial and wound-healing action of Ulmo honey (Eucryphia cordifolia) of differing degrees of purity
title_sort antibacterial and wound-healing action of ulmo honey (eucryphia cordifolia) of differing degrees of purity
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213365/
https://www.ncbi.nlm.nih.gov/pubmed/37252390
http://dx.doi.org/10.3389/fvets.2023.1172025
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