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A ubiquitination-mediated degradation system to target 14-3-3-binding phosphoproteins

The phosphorylation of 14-3-3 binding motif is involved in many cellular processes. A strategy that enables targeted degradation of 14-3-3-binding phosphoproteins (14-3-3-BPPs) for studying their functions is highly desirable for basic research. Here, we report a phosphorylation-induced, ubiquitin-p...

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Detalles Bibliográficos
Autores principales: Li, Zhaokai, Huang, Xiaoqiang, Li, Mohan, Chen, Y. Eugene, Wang, Zhong, Liu, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213371/
https://www.ncbi.nlm.nih.gov/pubmed/37251884
http://dx.doi.org/10.1016/j.heliyon.2023.e16318