A catalase inhibitor: Targeting the NADPH-binding site for castration-resistant prostate cancer therapy

Catalase (CAT) is an important antioxidant enzyme that breaks down H(2)O(2) into water and oxygen. Inhibitor-modulating CAT activity in cancer cells is emerging as a potential anticancer strategy. However, the discovery of CAT inhibitors towards the heme active center located at the bottom of long a...

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Detalles Bibliográficos
Autores principales: Cao, Ya Ya, Chen, Yuan Yuan, Wang, Ming Shu, Tong, Jing Jing, Xu, Meng, Zhao, Chi, Lin, Hong Yan, Mei, Long Can, Dong, Jin, Zhang, Wen Lin, Qin, Yu Xuan, Huang, Wei, Zhang, Dan, Yang, Guang Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213376/
https://www.ncbi.nlm.nih.gov/pubmed/37216701
http://dx.doi.org/10.1016/j.redox.2023.102751

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