PTPN2 targets TAK1 for dephosphorylation to improve cellular senescence and promote adipose tissue browning in T2DM

Introduction: The energy imbalance when energy intake exceeds expenditure acts as an essential factor in the development of insulin resistance (IR). The activity of brown adipose tissue, which is involved in the dissipation of energy via heat expenditure decreases under type 2 diabetic mellitus (T2D...

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Detalles Bibliográficos
Autores principales: Liu, Yapeng, Han, Lu, Zhu, Ping, Song, Ming, Zhang, Yaoyuan, Meng, Linlin, Zhang, Wei, Zhang, Cheng, Zhong, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213551/
https://www.ncbi.nlm.nih.gov/pubmed/37251330
http://dx.doi.org/10.3389/fphar.2023.1124633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213551/
https://www.ncbi.nlm.nih.gov/pubmed/37251330
http://dx.doi.org/10.3389/fphar.2023.1124633

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