The crosstalk between FGF21 and GH leads to weakened GH receptor signaling and IGF1 expression and is associated with growth failure in very preterm infants

BACKGROUND: Fibroblast growth factor 21 (FGF21) is an essential metabolic regulator that adapts to changes in nutritional status. Severe childhood undernutrition induces elevated FGF21 levels, contributing to growth hormone (GH) resistance and subsequent linear growth attenuation potentially through...

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Detalles Bibliográficos
Autores principales: Mistry, Jayna N., Silvennoinen, Sanna, Zaman, Farasat, Sävendahl, Lars, Mariniello, Katia, Hall, Charlotte, Howard, Sasha R., Dunkel, Leo, Sankilampi, Ulla, Guasti, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213667/
https://www.ncbi.nlm.nih.gov/pubmed/37251684
http://dx.doi.org/10.3389/fendo.2023.1105602

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