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Single cell RNA sequencing reveals distinct clusters of Irf8-expressing pulmonary conventional dendritic cells

A single population of interferon-regulatory factor 8 (Irf8)-dependent conventional dendritic cell (cDC type1) is considered to be responsible for both immunogenic and tolerogenic responses depending on the surrounding cytokine milieu. Here, we challenge this concept of an omnipotent single Irf8-dep...

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Detalles Bibliográficos
Autores principales: Jirmo, Adan Chari, Grychtol, Ruth, Gaedcke, Svenja, Liu, Bin, DeStefano, Stephanie, Happle, Christine, Halle, Olga, Monteiro, Joao T., Habener, Anika, Breiholz, Oliver D., DeLuca, David, Hansen, Gesine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213693/
https://www.ncbi.nlm.nih.gov/pubmed/37251386
http://dx.doi.org/10.3389/fimmu.2023.1127485

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