Supramolecular approaches for insulin stabilization without prolonged duration of action

Aggregation represents a significant challenge for the long-term formulation stability of insulin therapeutics. The supramolecular PEGylation of insulin with conjugates of cucurbit[7]uril and polyethylene glycol (CB[7]‒PEG) has been shown to stabilize insulin formulations by reducing aggregation pro...

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Detalles Bibliográficos
Autores principales: Meudom, Rolande, Zhang, Yanxian, VandenBerg, Michael A., Zou, Lei, Zhang, Yi Wolf, Webber, Matthew J., Chou, Danny Hung-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213764/
https://www.ncbi.nlm.nih.gov/pubmed/37250160
http://dx.doi.org/10.1016/j.apsb.2023.01.007

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