Perspective: Daniela Novick, cytokines and their receptors

This Perspective highlights the work of Dr. Daniela Novick in the field of cytokine biology. Using affinity chromatography to characterize cytokine-binding proteins, she identified soluble forms of the receptors as well as binding proteins for several cytokines, including tumor necrosis factor, inte...

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Autores principales: Ghezzi, Pietro, Fantuzzi, Giamila, Dinarello, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213776/
https://www.ncbi.nlm.nih.gov/pubmed/37251377
http://dx.doi.org/10.3389/fimmu.2023.1160651
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author Ghezzi, Pietro
Fantuzzi, Giamila
Dinarello, Charles A.
author_facet Ghezzi, Pietro
Fantuzzi, Giamila
Dinarello, Charles A.
author_sort Ghezzi, Pietro
collection PubMed
description This Perspective highlights the work of Dr. Daniela Novick in the field of cytokine biology. Using affinity chromatography to characterize cytokine-binding proteins, she identified soluble forms of the receptors as well as binding proteins for several cytokines, including tumor necrosis factor, interleukin (IL) 6, IL-18 and IL-32. Importantly, her work has been key in the development of monoclonal antibodies against interferons and cytokines. This Perspective discusses her contribution to the field and highlights her recent review on this topic.
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spelling pubmed-102137762023-05-27 Perspective: Daniela Novick, cytokines and their receptors Ghezzi, Pietro Fantuzzi, Giamila Dinarello, Charles A. Front Immunol Immunology This Perspective highlights the work of Dr. Daniela Novick in the field of cytokine biology. Using affinity chromatography to characterize cytokine-binding proteins, she identified soluble forms of the receptors as well as binding proteins for several cytokines, including tumor necrosis factor, interleukin (IL) 6, IL-18 and IL-32. Importantly, her work has been key in the development of monoclonal antibodies against interferons and cytokines. This Perspective discusses her contribution to the field and highlights her recent review on this topic. Frontiers Media S.A. 2023-05-11 /pmc/articles/PMC10213776/ /pubmed/37251377 http://dx.doi.org/10.3389/fimmu.2023.1160651 Text en Copyright © 2023 Ghezzi, Fantuzzi and Dinarello https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Ghezzi, Pietro
Fantuzzi, Giamila
Dinarello, Charles A.
Perspective: Daniela Novick, cytokines and their receptors
title Perspective: Daniela Novick, cytokines and their receptors
title_full Perspective: Daniela Novick, cytokines and their receptors
title_fullStr Perspective: Daniela Novick, cytokines and their receptors
title_full_unstemmed Perspective: Daniela Novick, cytokines and their receptors
title_short Perspective: Daniela Novick, cytokines and their receptors
title_sort perspective: daniela novick, cytokines and their receptors
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213776/
https://www.ncbi.nlm.nih.gov/pubmed/37251377
http://dx.doi.org/10.3389/fimmu.2023.1160651
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