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A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies
Magnetic resonance imaging (MRI) of the brain is commonly used to detect where chronic and active lesions are in multiple sclerosis (MS). MRI is also extensively used as a tool to calculate and extrapolate brain health by way of volumetric analysis or advanced imaging techniques. In MS patients, psy...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213782/ https://www.ncbi.nlm.nih.gov/pubmed/37250694 http://dx.doi.org/10.3389/fnhum.2023.1151531 |
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author | Brasanac, Jelena Chien, Claudia |
author_facet | Brasanac, Jelena Chien, Claudia |
author_sort | Brasanac, Jelena |
collection | PubMed |
description | Magnetic resonance imaging (MRI) of the brain is commonly used to detect where chronic and active lesions are in multiple sclerosis (MS). MRI is also extensively used as a tool to calculate and extrapolate brain health by way of volumetric analysis or advanced imaging techniques. In MS patients, psychiatric symptoms are common comorbidities, with depression being the main one. Even though these symptoms are a major determinant of quality of life in MS, they are often overlooked and undertreated. There has been evidence of bidirectional interactions between the course of MS and comorbid psychiatric symptoms. In order to mitigate disability progression in MS, treating psychiatric comorbidities should be investigated and optimized. New research for the prediction of disease states or phenotypes of disability have advanced, primarily due to new technologies and a better understanding of the aging brain. |
format | Online Article Text |
id | pubmed-10213782 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102137822023-05-27 A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies Brasanac, Jelena Chien, Claudia Front Hum Neurosci Neuroscience Magnetic resonance imaging (MRI) of the brain is commonly used to detect where chronic and active lesions are in multiple sclerosis (MS). MRI is also extensively used as a tool to calculate and extrapolate brain health by way of volumetric analysis or advanced imaging techniques. In MS patients, psychiatric symptoms are common comorbidities, with depression being the main one. Even though these symptoms are a major determinant of quality of life in MS, they are often overlooked and undertreated. There has been evidence of bidirectional interactions between the course of MS and comorbid psychiatric symptoms. In order to mitigate disability progression in MS, treating psychiatric comorbidities should be investigated and optimized. New research for the prediction of disease states or phenotypes of disability have advanced, primarily due to new technologies and a better understanding of the aging brain. Frontiers Media S.A. 2023-05-11 /pmc/articles/PMC10213782/ /pubmed/37250694 http://dx.doi.org/10.3389/fnhum.2023.1151531 Text en Copyright © 2023 Brasanac and Chien. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Brasanac, Jelena Chien, Claudia A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies |
title | A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies |
title_full | A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies |
title_fullStr | A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies |
title_full_unstemmed | A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies |
title_short | A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies |
title_sort | review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213782/ https://www.ncbi.nlm.nih.gov/pubmed/37250694 http://dx.doi.org/10.3389/fnhum.2023.1151531 |
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