Universal chimeric Fcγ receptor T cells with appropriate affinity for IgG1 antibody exhibit optimal antitumor efficacy

Developing universal CARs with improved flexible targeting and controllable activities is urgently needed. While several studies have suggested the potential of CD16a in tandem with monoclonal antibodies to construct universal CAR-T cells, the weak affinity between them is one of the limiting factor...

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Detalles Bibliográficos
Autores principales: Zhu, Wen, Wang, Yang, Lv, Liangyin, Wang, Hui, Shi, Wenqiang, Liu, Zexin, Zhou, Mingzhe, Zhu, Jianwei, Lu, Huili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213811/
https://www.ncbi.nlm.nih.gov/pubmed/37250170
http://dx.doi.org/10.1016/j.apsb.2023.02.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213811/
https://www.ncbi.nlm.nih.gov/pubmed/37250170
http://dx.doi.org/10.1016/j.apsb.2023.02.004

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