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From bugs to drugs: Bacterial 3-IAA enhances efficacy of chemotherapy in pancreatic cancer
Tintelnot et al.(1) identified enrichment of indole-3-acetic acid (3-IAA), a tryptophan metabolite produced by gut microbiota, as a predictor of chemotherapy response in pancreatic adenocarcinoma. Recapitulated in mouse models, 3-IAA represents a novel potential therapeutic approach for chemotherapy...
Autores principales: | Seo, Y. David, Wargo, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213830/ https://www.ncbi.nlm.nih.gov/pubmed/37196631 http://dx.doi.org/10.1016/j.xcrm.2023.101039 |
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