Learning while treating: Gain-of-function STAT6 variants in severe allergic disease

In an era of rapid identification of inborn errors of immunity, Sharma et al.(1) report novel heterozygous gain-of-function variants in the signal transducer and activator of transcription 6 (STAT6) gene in individuals with severe and early onset multi-systemic allergic disease.

Detalles Bibliográficos
Autores principales: Smith, Tukisa D., Doherty, Taylor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213836/
https://www.ncbi.nlm.nih.gov/pubmed/37196636
http://dx.doi.org/10.1016/j.xcrm.2023.101040
Descripción
Sumario:In an era of rapid identification of inborn errors of immunity, Sharma et al.(1) report novel heterozygous gain-of-function variants in the signal transducer and activator of transcription 6 (STAT6) gene in individuals with severe and early onset multi-systemic allergic disease.

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