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The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis

Innate lymphoid cells (ILCs) are considered innate counterparts of adaptive T cells; however, their common and unique transcriptional signatures in pediatric inflammatory bowel disease (pIBD) are largely unknown. Here, we report a dysregulated colonic ILC composition in pIBD colitis that correlates...

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Detalles Bibliográficos
Autores principales: Kokkinou, Efthymia, Soini, Tea, Pandey, Ram Vinay, van Acker, Aline, Theorell, Jakob, Czarnewski, Paulo, Kvedaraite, Egle, Vandamme, Niels, Lourda, Magda, Sorini, Chiara, Weigel, Whitney, Carrasco, Anna, Tibbitt, Christopher Andrew, Schlums, Heinrich, Lindforss, Ulrik, Nordenvall, Caroline, Ljunggren, Malin, Ideström, Maja, Svensson, Mattias, Henter, Jan-Inge, Villablanca, Eduardo J., Bryceson, Yenan T., Rolandsdotter, Helena, Mjösberg, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213874/
https://www.ncbi.nlm.nih.gov/pubmed/37160121
http://dx.doi.org/10.1016/j.xcrm.2023.101038