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The design and evaluation of the outflow structures of an interventional microaxial blood pump

Blood pump design efforts are focused on enhancing hydraulic effectiveness and minimizing shear stress. Unlike conventional blood pumps, interventional microaxial blood pumps have a unique outflow structure due to minimally invasive technology. The outflow structure, composed of the diffuser and cag...

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Autores principales: Yun, Zhong, Yao, Jinfu, Wang, Liang, Tang, Xiaoyan, Feng, Yunhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213901/
https://www.ncbi.nlm.nih.gov/pubmed/37250127
http://dx.doi.org/10.3389/fphys.2023.1169905
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author Yun, Zhong
Yao, Jinfu
Wang, Liang
Tang, Xiaoyan
Feng, Yunhao
author_facet Yun, Zhong
Yao, Jinfu
Wang, Liang
Tang, Xiaoyan
Feng, Yunhao
author_sort Yun, Zhong
collection PubMed
description Blood pump design efforts are focused on enhancing hydraulic effectiveness and minimizing shear stress. Unlike conventional blood pumps, interventional microaxial blood pumps have a unique outflow structure due to minimally invasive technology. The outflow structure, composed of the diffuser and cage bridges, is crucial in minimizing the pump size to provide adequate hemodynamic support. This study proposed four outflow structures of an interventional microaxial blood pump depending on whether the diffuser with or without blades and cage bridges were straight or curved. The outflow flow structure’s effect on the blood pump’s hydraulic performance and shear stress distribution was evaluated by computational fluid dynamics and hydraulic experiments. The results showed that all four outflow structures could achieve the pressure and flow requirements specified at the design point but with significant differences in shear stress distribution. Among them, the outflow structure with curved bridges would make the blood dispersed more evenly when flowing out of the pump, which could effectively reduce the shear stress at the cage bridges. The outflow structure with blades would aggravate the secondary flow at the leading edge of the impeller, increasing the risk of flow stagnation. The combination of curved bridges and the bladeless diffuser had a relatively better shear stress distribution, with the proportion of fluid exposed to low scalar shear stress (<50 Pa) and high scalar shear stress (>150 Pa) in the blood pump being 97.92% and 0.26%, respectively. It could be concluded that the outflow structure with curved bridges and bladeless diffuser exhibited relatively better shear stress distribution and a lower hemolysis index of 0.00648%, which could support continued research on optimizing the microaxial blood pumps.
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spelling pubmed-102139012023-05-27 The design and evaluation of the outflow structures of an interventional microaxial blood pump Yun, Zhong Yao, Jinfu Wang, Liang Tang, Xiaoyan Feng, Yunhao Front Physiol Physiology Blood pump design efforts are focused on enhancing hydraulic effectiveness and minimizing shear stress. Unlike conventional blood pumps, interventional microaxial blood pumps have a unique outflow structure due to minimally invasive technology. The outflow structure, composed of the diffuser and cage bridges, is crucial in minimizing the pump size to provide adequate hemodynamic support. This study proposed four outflow structures of an interventional microaxial blood pump depending on whether the diffuser with or without blades and cage bridges were straight or curved. The outflow flow structure’s effect on the blood pump’s hydraulic performance and shear stress distribution was evaluated by computational fluid dynamics and hydraulic experiments. The results showed that all four outflow structures could achieve the pressure and flow requirements specified at the design point but with significant differences in shear stress distribution. Among them, the outflow structure with curved bridges would make the blood dispersed more evenly when flowing out of the pump, which could effectively reduce the shear stress at the cage bridges. The outflow structure with blades would aggravate the secondary flow at the leading edge of the impeller, increasing the risk of flow stagnation. The combination of curved bridges and the bladeless diffuser had a relatively better shear stress distribution, with the proportion of fluid exposed to low scalar shear stress (<50 Pa) and high scalar shear stress (>150 Pa) in the blood pump being 97.92% and 0.26%, respectively. It could be concluded that the outflow structure with curved bridges and bladeless diffuser exhibited relatively better shear stress distribution and a lower hemolysis index of 0.00648%, which could support continued research on optimizing the microaxial blood pumps. Frontiers Media S.A. 2023-05-11 /pmc/articles/PMC10213901/ /pubmed/37250127 http://dx.doi.org/10.3389/fphys.2023.1169905 Text en Copyright © 2023 Yun, Yao, Wang, Tang and Feng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Yun, Zhong
Yao, Jinfu
Wang, Liang
Tang, Xiaoyan
Feng, Yunhao
The design and evaluation of the outflow structures of an interventional microaxial blood pump
title The design and evaluation of the outflow structures of an interventional microaxial blood pump
title_full The design and evaluation of the outflow structures of an interventional microaxial blood pump
title_fullStr The design and evaluation of the outflow structures of an interventional microaxial blood pump
title_full_unstemmed The design and evaluation of the outflow structures of an interventional microaxial blood pump
title_short The design and evaluation of the outflow structures of an interventional microaxial blood pump
title_sort design and evaluation of the outflow structures of an interventional microaxial blood pump
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213901/
https://www.ncbi.nlm.nih.gov/pubmed/37250127
http://dx.doi.org/10.3389/fphys.2023.1169905
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