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Air pollution, EGFR mutation, and cancer initiation

Swanton et al.(1) find that PM(2.5) exposure is associated with EGFR/KRAS-driven lung cancer incidence. PM(2.5) increases EGFR pre-mutated alveolar type II cell progenitor function and tumorigenic activity through interstitial macrophage-secreted IL-1β, providing potential prevention approaches to i...

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Detalles Bibliográficos
Autores principales:	Han, Si-Chong, Wang, Gui-Zhen, Zhou, Guang-Biao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Spotlight
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213952/ https://www.ncbi.nlm.nih.gov/pubmed/37196632 http://dx.doi.org/10.1016/j.xcrm.2023.101046

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