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An overview of the management of osteoporosis in the aging female population

Osteoporosis is a systemic skeletal disease that is a cause of morbidity and mortality. It can affect all ages but most frequently postmenopausal women. It is a silent condition, however, osteoporotic fractures can lead to significant pain and disability. In this review article, we aim to review the...

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Autores principales: Amin, Usman, McPartland, Aoife, O’Sullivan, Miriam, Silke, Carmel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214060/
https://www.ncbi.nlm.nih.gov/pubmed/37218715
http://dx.doi.org/10.1177/17455057231176655
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author Amin, Usman
McPartland, Aoife
O’Sullivan, Miriam
Silke, Carmel
author_facet Amin, Usman
McPartland, Aoife
O’Sullivan, Miriam
Silke, Carmel
author_sort Amin, Usman
collection PubMed
description Osteoporosis is a systemic skeletal disease that is a cause of morbidity and mortality. It can affect all ages but most frequently postmenopausal women. It is a silent condition, however, osteoporotic fractures can lead to significant pain and disability. In this review article, we aim to review the clinical approach to the management of postmenopausal osteoporosis. We include risk assessment, investigations, and the various pharmacological and non-pharmacological options used in the treatment of osteoporosis. We have discussed the pharmacological options individually including their mechanism of action, safety profile, effects on bone mineral density and fracture risks, and duration of use. Potential new treatments are also discussed. The importance of sequence in the use of osteoporotic medicine is also highlighted in the article. An understanding of the different treatment options will hopefully help in the management of this very common and debilitating condition.
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spelling pubmed-102140602023-05-27 An overview of the management of osteoporosis in the aging female population Amin, Usman McPartland, Aoife O’Sullivan, Miriam Silke, Carmel Womens Health (Lond) Cardiovascular and Metabolic Bone Health in Aging Women Osteoporosis is a systemic skeletal disease that is a cause of morbidity and mortality. It can affect all ages but most frequently postmenopausal women. It is a silent condition, however, osteoporotic fractures can lead to significant pain and disability. In this review article, we aim to review the clinical approach to the management of postmenopausal osteoporosis. We include risk assessment, investigations, and the various pharmacological and non-pharmacological options used in the treatment of osteoporosis. We have discussed the pharmacological options individually including their mechanism of action, safety profile, effects on bone mineral density and fracture risks, and duration of use. Potential new treatments are also discussed. The importance of sequence in the use of osteoporotic medicine is also highlighted in the article. An understanding of the different treatment options will hopefully help in the management of this very common and debilitating condition. SAGE Publications 2023-05-23 /pmc/articles/PMC10214060/ /pubmed/37218715 http://dx.doi.org/10.1177/17455057231176655 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Cardiovascular and Metabolic Bone Health in Aging Women
Amin, Usman
McPartland, Aoife
O’Sullivan, Miriam
Silke, Carmel
An overview of the management of osteoporosis in the aging female population
title An overview of the management of osteoporosis in the aging female population
title_full An overview of the management of osteoporosis in the aging female population
title_fullStr An overview of the management of osteoporosis in the aging female population
title_full_unstemmed An overview of the management of osteoporosis in the aging female population
title_short An overview of the management of osteoporosis in the aging female population
title_sort overview of the management of osteoporosis in the aging female population
topic Cardiovascular and Metabolic Bone Health in Aging Women
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214060/
https://www.ncbi.nlm.nih.gov/pubmed/37218715
http://dx.doi.org/10.1177/17455057231176655
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