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An overview of the management of osteoporosis in the aging female population
Osteoporosis is a systemic skeletal disease that is a cause of morbidity and mortality. It can affect all ages but most frequently postmenopausal women. It is a silent condition, however, osteoporotic fractures can lead to significant pain and disability. In this review article, we aim to review the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214060/ https://www.ncbi.nlm.nih.gov/pubmed/37218715 http://dx.doi.org/10.1177/17455057231176655 |
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author | Amin, Usman McPartland, Aoife O’Sullivan, Miriam Silke, Carmel |
author_facet | Amin, Usman McPartland, Aoife O’Sullivan, Miriam Silke, Carmel |
author_sort | Amin, Usman |
collection | PubMed |
description | Osteoporosis is a systemic skeletal disease that is a cause of morbidity and mortality. It can affect all ages but most frequently postmenopausal women. It is a silent condition, however, osteoporotic fractures can lead to significant pain and disability. In this review article, we aim to review the clinical approach to the management of postmenopausal osteoporosis. We include risk assessment, investigations, and the various pharmacological and non-pharmacological options used in the treatment of osteoporosis. We have discussed the pharmacological options individually including their mechanism of action, safety profile, effects on bone mineral density and fracture risks, and duration of use. Potential new treatments are also discussed. The importance of sequence in the use of osteoporotic medicine is also highlighted in the article. An understanding of the different treatment options will hopefully help in the management of this very common and debilitating condition. |
format | Online Article Text |
id | pubmed-10214060 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-102140602023-05-27 An overview of the management of osteoporosis in the aging female population Amin, Usman McPartland, Aoife O’Sullivan, Miriam Silke, Carmel Womens Health (Lond) Cardiovascular and Metabolic Bone Health in Aging Women Osteoporosis is a systemic skeletal disease that is a cause of morbidity and mortality. It can affect all ages but most frequently postmenopausal women. It is a silent condition, however, osteoporotic fractures can lead to significant pain and disability. In this review article, we aim to review the clinical approach to the management of postmenopausal osteoporosis. We include risk assessment, investigations, and the various pharmacological and non-pharmacological options used in the treatment of osteoporosis. We have discussed the pharmacological options individually including their mechanism of action, safety profile, effects on bone mineral density and fracture risks, and duration of use. Potential new treatments are also discussed. The importance of sequence in the use of osteoporotic medicine is also highlighted in the article. An understanding of the different treatment options will hopefully help in the management of this very common and debilitating condition. SAGE Publications 2023-05-23 /pmc/articles/PMC10214060/ /pubmed/37218715 http://dx.doi.org/10.1177/17455057231176655 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Cardiovascular and Metabolic Bone Health in Aging Women Amin, Usman McPartland, Aoife O’Sullivan, Miriam Silke, Carmel An overview of the management of osteoporosis in the aging female population |
title | An overview of the management of osteoporosis in the aging female
population |
title_full | An overview of the management of osteoporosis in the aging female
population |
title_fullStr | An overview of the management of osteoporosis in the aging female
population |
title_full_unstemmed | An overview of the management of osteoporosis in the aging female
population |
title_short | An overview of the management of osteoporosis in the aging female
population |
title_sort | overview of the management of osteoporosis in the aging female
population |
topic | Cardiovascular and Metabolic Bone Health in Aging Women |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214060/ https://www.ncbi.nlm.nih.gov/pubmed/37218715 http://dx.doi.org/10.1177/17455057231176655 |
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