Cargando…
The membrane electric field regulates the PIP(2)-binding site to gate the KCNQ1 channel
Voltage-dependent ion channels underlie the propagation of action potentials and other forms of electrical activity in cells. In these proteins, voltage sensor domains (VSDs) regulate opening and closing of the pore through the displacement of their positive-charged S4 helix in response to the membr...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214144/ https://www.ncbi.nlm.nih.gov/pubmed/37192161 http://dx.doi.org/10.1073/pnas.2301985120 |