COVID-19-related hyperglycemia is associated with infection of hepatocytes and stimulation of gluconeogenesis

Occurrence of hyperglycemia upon infection is associated with worse clinical outcome in COVID-19 patients. However, it is still unknown whether SARS-CoV-2 directly triggers hyperglycemia. Herein, we interrogated whether and how SARS-CoV-2 causes hyperglycemia by infecting hepatocytes and increasing...

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Detalles Bibliográficos
Autores principales: Barreto, Ester A., Cruz, Amanda S., Veras, Flavio P., Martins, Ronaldo, Bernardelli, Rafaella S., Paiva, Isadora M., Lima, Thais M., Singh, Youvika, Guimarães, Raphael C., Damasceno, Samara, Pereira, Nayara, Alves, João Manoel, Gonçalves, Tiago T., Forato, Julia, Muraro, Stéfanie P., Souza, Gabriela F., Batah, Sabrina Setembre, Proenca-Modena, José L., Mori, Marcelo A., Cunha, Fernando Q., Louzada-Junior, Paulo, Cunha, Thiago M., Nakaya, Helder I., Fabro, Alexandre, de Oliveira, Renê D. R., Arruda, Eurico, Réa, Rosângela, Réa Neto, Álvaro, Fernandes da Silva, Miguel M., Leiria, Luiz Osório
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214153/
https://www.ncbi.nlm.nih.gov/pubmed/37186819
http://dx.doi.org/10.1073/pnas.2217119120

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