Reverse-QTY code design of active human serum albumin self-assembled amphiphilic nanoparticles for effective anti-tumor drug doxorubicin release in mice

Human serum albumin (HSA) is a highly water-soluble protein with 67% alpha-helix content and three distinct domains (I, II, and III). HSA offers a great promise in drug delivery with enhanced permeability and retention effect. But it is hindered by protein denaturation during drug entrapment or conj...

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Detalles Bibliográficos
Autores principales: Meng, Run, Hao, Shilei, Sun, Changfa, Hou, Zongkun, Hou, Yao, Wang, Lili, Deng, Peiying, Deng, Jia, Yang, Yaying, Xia, Haijian, Wang, Bochu, Qing, Rui, Zhang, Shuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214157/
https://www.ncbi.nlm.nih.gov/pubmed/37186820
http://dx.doi.org/10.1073/pnas.2220173120

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