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Astrocytic control of extracellular GABA drives circadian timekeeping in the suprachiasmatic nucleus
The hypothalamic suprachiasmatic nucleus (SCN) is the master mammalian circadian clock. Its cell-autonomous timing mechanism, a transcriptional/translational feedback loop (TTFL), drives daily peaks of neuronal electrical activity, which in turn control circadian behavior. Intercellular signals, med...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214171/ https://www.ncbi.nlm.nih.gov/pubmed/37186824 http://dx.doi.org/10.1073/pnas.2301330120 |