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Astrocytic control of extracellular GABA drives circadian timekeeping in the suprachiasmatic nucleus

The hypothalamic suprachiasmatic nucleus (SCN) is the master mammalian circadian clock. Its cell-autonomous timing mechanism, a transcriptional/translational feedback loop (TTFL), drives daily peaks of neuronal electrical activity, which in turn control circadian behavior. Intercellular signals, med...

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Detalles Bibliográficos
Autores principales: Patton, Andrew P., Morris, Emma L., McManus, David, Wang, Huan, Li, Yulong, Chin, Jason W., Hastings, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214171/
https://www.ncbi.nlm.nih.gov/pubmed/37186824
http://dx.doi.org/10.1073/pnas.2301330120