SMARCB1 regulates the hypoxic stress response in sickle cell trait

Renal medullary carcinoma (RMC) is an aggressive kidney cancer that almost exclusively develops in individuals with sickle cell trait (SCT) and is always characterized by loss of the tumor suppressor SMARCB1. Because renal ischemia induced by red blood cell sickling exacerbates chronic renal medulla...

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Detalles Bibliográficos
Autores principales: Soeung, Melinda, Perelli, Luigi, Chen, Ziheng, Dondossola, Eleonora, Ho, I-Lin, Carbone, Federica, Zhang, Li, Khan, Hania, Le, Courtney N., Zhu, Cihui, Peoples, Michael D., Feng, Ningping, Jiang, Shan, Zacharias, Niki Millward, Minelli, Rosalba, Shapiro, Daniel D., Deem, Angela K., Gao, Sisi, Cheng, Emily H., Lucchetti, Donatella, Walker, Cheryl L., Carugo, Alessandro, Giuliani, Virginia, Heffernan, Timothy P., Viale, Andrea, Tannir, Nizar M., Draetta, Giulio F., Msaouel, Pavlos, Genovese, Giannicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214195/
https://www.ncbi.nlm.nih.gov/pubmed/37186844
http://dx.doi.org/10.1073/pnas.2209639120

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