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Sequential absorption of two photons creates a bistable form of RubyACR responsible for its strong desensitization

Channelrhodopsins with red-shifted absorption, rare in nature, are highly desired for optogenetics because light of longer wavelengths more deeply penetrates biological tissue. RubyACRs (Anion ChannelRhodopsins), a group of four closely related anion-conducting channelrhodopsins from thraustochytrid...

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Detalles Bibliográficos
Autores principales: Sineshchekov, Oleg A., Govorunova, Elena G., Li, Hai, Wang, Yumei, Spudich, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214203/
https://www.ncbi.nlm.nih.gov/pubmed/37186849
http://dx.doi.org/10.1073/pnas.2301521120

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