A dual-action niclosamide-based prodrug that targets cancer stem cells and inhibits TNBC metastasis

Chemotherapy typically destroys the tumor mass but rarely eradicates the cancer stem cells (CSCs) that can drive metastatic recurrence. A key current challenge is finding ways to eradicate CSCs and suppress their characteristics. Here, we report a prodrug, Nic-A, created by combining a carbonic anhy...

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Detalles Bibliográficos
Autores principales: Kim, Ji Hyeon, Park, Soeun, Jung, Eunsun, Shin, Jinwoo, Kim, Yoon-Jae, Kim, Ji Young, Sessler, Jonathan L., Seo, Jae Hong, Kim, Jong Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214212/
https://www.ncbi.nlm.nih.gov/pubmed/37186828
http://dx.doi.org/10.1073/pnas.2304081120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214212/
https://www.ncbi.nlm.nih.gov/pubmed/37186828
http://dx.doi.org/10.1073/pnas.2304081120

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