ANPELA: Significantly Enhanced Quantification Tool for Cytometry‐Based Single‐Cell Proteomics (Adv. Sci. 15/2023)

Single‐Cell Proteomics Single‐cell proteomics provides an unprecedented view of cellular heterogeneity at the single‐cell resolution, enabling a better understanding of biological mechanisms. In article number 2207061, Ying Zhang, Huaicheng Sun, Feng Zhu, and co‐workers develop ANPELA, a significantly enhanced quantification tool that facilitates the analysis of high‐dimensional single‐cell proteome expression data and the identification of cell populations with distinct static or pseudo‐temporal phenotypes. This work sheds light on the importance of accurate quantification and proper data processing in advancing single‐cell proteomics research. [Image: see text]