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Regulating Type H Vessel Formation and Bone Metabolism via Bone‐Targeting Oral Micro/Nano‐Hydrogel Microspheres to Prevent Bone Loss (Adv. Sci. 15/2023)

Osteoporosis A pH‐responsive shell‐core structured micro/nano‐hydrogel microspheres construct via gas microfluidics and ionic cross‐linking technique. The microspheres can achieve oral delivery, intragastric protection, intestinal slow/controlled release, and active targeting to bone tissue. This no...

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Detalles Bibliográficos
Autores principales: Li, Junjie, Wei, Gang, Liu, Gongwen, Du, Yawei, Zhang, Ruizhi, Wang, Aifei, Liu, Baoshan, Cui, Wenguo, Jia, Peng, Xu, Youjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214228/
http://dx.doi.org/10.1002/advs.202370093
Descripción
Sumario:Osteoporosis A pH‐responsive shell‐core structured micro/nano‐hydrogel microspheres construct via gas microfluidics and ionic cross‐linking technique. The microspheres can achieve oral delivery, intragastric protection, intestinal slow/controlled release, and active targeting to bone tissue. This novel oral microspheres can simultaneously accelerate intraosseous vascularization and decrease bone resorption, offering a brand‐new approach to prevent postmenopausal osteoporosis. More details can be found in article number 2207381 by Wenguo Cui, Peng Jia, Youjia Xu, and co‐workers. [Image: see text]