The Imbalance of p53–Park7 Signaling Axis Induces Iron Homeostasis Dysfunction in Doxorubicin‐Challenged Cardiomyocytes

Doxorubicin (DOX)‐induced cardiotoxicity (DoIC) is a major side effect for cancer patients. Recently, ferroptosis, triggered by iron overload, is demonstrated to play a role in DoIC. How iron homeostasis is dysregulated in DoIC remains to be elucidated. Here, the authors demonstrate that DOX challen...

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Detalles Bibliográficos
Autores principales: Pan, Jianan, Xiong, Weiyao, Zhang, Alian, Zhang, Hui, Lin, Hao, Gao, Lin, Ke, Jiahan, Huang, Shuying, Zhang, Junfeng, Gu, Jun, Chang, Alex Chia Yu, Wang, Changqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214246/
https://www.ncbi.nlm.nih.gov/pubmed/36967569
http://dx.doi.org/10.1002/advs.202206007

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