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Glucocorticoid-mediated induction of ZBTB16 affects insulin secretion in human islets and EndoC-βH1 β-cells

Glucocorticoid use is associated with steroid-induced diabetes mellitus and impaired pancreatic β-cell insulin secretion. Here, the glucocorticoid-mediated transcriptomic changes in human pancreatic islets and the human insulin-secreting EndoC-βH1 cells were investigated to uncover genes involved in...

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Detalles Bibliográficos
Autores principales: Karagiannopoulos, Alexandros, Westholm, Efraim, Ofori, Jones K., Cowan, Elaine, Esguerra, Jonathan L.S., Eliasson, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214295/
https://www.ncbi.nlm.nih.gov/pubmed/37250333
http://dx.doi.org/10.1016/j.isci.2023.106555